Painful Joints and Body Weakness? It Could Be Lupus

Peace Nwoha |Apr 1, 2021

Do I Have Lupus?

Your body has an immune system that defends it from germs and foreign bodies. Sometimes, your body’s defense system mistakes some of the cells in your body for germs and begins to fight them. This is called an autoimmune disease, and lupus is just one example.

Lupus is a long-term autoimmune condition with alternating periods of mild to severe symptoms that cause pain and inflammation within your body. The most commonly affected areas include the skin, organs such as the lungs, kidneys, heart, and joints.

The Lupus Foundation stated that about 1.5 million Americans have been diagnosed with the condition. However, the figure might be higher if you consider cases that have not been reported. Lupus affects all age groups but has been found to have a higher incidence among women between the ages of 15 to 44, individuals with a family history of other autoimmune conditions or lupus, and some ethnic groups, including Hispanic, Native American, African American, and Asian American.

Types of Lupus

This article focuses on systemic lupus erythematosus (SLE), as it is the most common type. When someone is talking about lupus, they are usually referring to SLE. However, there are four different types:

  • Systemic lupus erythematosus (SLE) — the most common type, affecting 70% of people with lupus.
  • Cutaneous — limited to the skin, causing rashes or sores (lesions). Approximately two-thirds of people with lupus will develop a form of cutaneous lupus.
  • Drug-induced — a lupus-like disease caused by certain prescription medications. This type is more common in men.
  • Neonatal — not true lupus, but a rare condition that affects the fetus and infant of a mother with lupus.

Symptoms of Lupus

The symptoms associated with systemic lupus erythematosus (SLE) include:

  • Body weakness
  • Loss of hair
  • Pain and swelling in the joints
  • A characteristic rash that spreads across the nose and cheeks commonly referred to as a “butterfly rash"
  • Headaches
  • Delayed wound healing
  • Raynaud’s phenomenon in which the fingers turn blue or white when exposed to cold

The symptoms may develop slowly, and no two cases are exactly alike. They may be temporary or permanent, and they can range from mild to severe. The signs and symptoms are similar to those of other systemic conditions, so careful assessment is needed to diagnose properly.

Causes

The cause of this condition is still unknown, but some factors have been linked to the condition.

Estrogen Hormone

Lupus has been noted to occur more in females than males with worsened symptoms during menstruation and pregnancy. These findings have prompted clinicians to link estrogen with the condition.

Heredity

Although no gene is associated with the condition so far, it has been observed that individuals with this condition tend to have members of their family who also have other autoimmune issues.

Environmental Triggers

These can be from physical or emotional trauma, infections, medications, and radiation.

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How to Manage Lupus

Management begins with an appropriate diagnosis. This usually includes your doctor taking a medical history to determine when the symptoms started, their frequency, duration, and severity.

A thorough physical examination is then conducted to identify the signs of the condition, such as:

  • Thinning or loss of hair
  • Tenderness and joint swelling
  • Butterfly or malar rash
  • Oral or nasal ulcers
  • Pain or difficulty breathing which may indicate lung involvement
  • Irregularities in heartbeat or function which could indicate heart involvement

Several screening tests may be done, including a chest x-ray, electrocardiogram (ECG or EKG), urinalysis, blood tests, and tests for other specific areas that could be affected, such as the abdomen.

Treatment Options

As of today, there is still no cure for lupus. The condition can only be managed long-term through:

  • Non-steroidal anti-inflammatory medications (NSAIDs) and antimalarial medications to relieve joint pain and tenderness
  • Corticosteroids to stabilize the immune system
  • Steroid-based creams for butterfly rashes
  • In severe cases, medications that specifically target the immune system are often prescribed

You may also get referred to specialists who will help manage affected parts of your body, such as a cardiologist or rheumatologist. You should also ensure that you modify your lifestyle to reduce stress and environmental triggers and drink lots of water.

Complications

Lupus can cause severe pregnancy complications, sometimes resulting in miscarriage, so it is essential to involve your doctor throughout your pregnancy and delivery process. Since the condition affects the immune system in various parts of the body, long-term effects can manifest in several ways, such as:

  • Blood clots could get dislodged and block narrow blood vessels leading to loss of function of the affected organ
  • Inflamed blood vessels, lungs, and kidneys
  • Lung or Kidney failure
  • Memory loss
  • Alopecia or baldness
  • Heart attack
  • Stroke
  • Seizures

What is the Prognosis?

The prognosis for lupus varies because it affects everyone differently. Nonetheless, it is crucial that you begin managing the condition early. Do not hesitate to let your health care provider know about any new symptoms, pregnancy, or issues that may be bothering you.

Systemic lupus erythematosus is a long-term condition, and managing it can sometimes negatively affect mental health. Make sure to seek counseling and support when necessary, and try not to work under stressful conditions or in environments that can be detrimental to your health and well-being.

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The Best Approaches to Seizure Control in Dravet Syndrome

Aisha Patel | April 1, 2021

Dravet Syndrome Seizure Treatment Options People with Dravet Syndrome often experience a variety of different types of seizures, including prolonged ones. To help, there's Fintepla, a medication approved to treat seizures caused by Dravet syndrome. Fintepla Fintepla works by targeting the brain’s electrical activity, helping to reduce the number and severity of seizures. Doctors prescribe Fintepla when other medications haven’t been effective in controlling seizures. This treatment has shown positive results in many patients, making it an essential option for managing Dravet syndrome. Medications for Dravet Syndrome Seizures Clobazam: This drug is often prescribed alongside other treatments. It helps to control seizures by calming the brain and reducing electrical activity. Valproate: This medication is used to control a variety of seizure types. However, it is not always the best choice for younger children due to its potential side effects. Topiramate: Used to prevent seizures, this medication works by affecting the brain's electrical signals. [youmaylike] Doctors may need to try different combinations of medications to find what works best for the individual. It’s important for patients and their families to closely monitor the medications and any side effects. Dietary Approaches: The Ketogenic Diet For some individuals with Dravet Syndrome, medications may not be enough to control seizures. In these cases, dietary treatments, such as the ketogenic diet, can be very helpful. The ketogenic diet is high in fats and low in carbohydrates, and it forces the body to use fat for energy instead of carbohydrates. This change in metabolism can help reduce seizures. The ketogenic diet should only be followed under the supervision of a doctor or dietitian, as it requires careful planning to ensure that the person gets the proper nutrition. Some children with Dravet Syndrome may experience a significant reduction in seizures after starting the ketogenic diet. Vagus Nerve Stimulation (VNS) Vagus Nerve Stimulation (VNS) is another treatment option for Dravet Syndrome. This therapy involves implanting a small device under the skin in the chest. The device sends electrical signals to the brain through the vagus nerve, which can help reduce the frequency and severity of seizures. The device can be programmed to give a burst of electrical stimulation when a seizure is detected, helping to stop the seizure or make it less severe. VNS is often considered when medications and diet do not provide enough seizure control. It is typically used in combination with other treatments. Surgical Options In some rare cases, surgery may be an option for treating Dravet Syndrome. If seizures are only coming from one part of the brain and medications do not help, surgery may be performed to remove that part of the brain. This surgery is called a lobectomy or hemispherectomy, depending on the area of the brain involved. Surgical options are not suitable for everyone, and doctors will carefully evaluate the risks and benefits before recommending surgery. Supportive Therapies While medications and other treatments are important for managing seizures, other therapies can be helpful in improving quality of life for individuals with Dravet Syndrome. These may include: Physical therapy: This helps improve mobility and strength, which can be affected by seizures. Occupational therapy: Helps individuals learn daily skills to live as independently as possible. Speech therapy: Helps improve communication skills, which may be affected by seizures. Ongoing Monitoring and Care Managing Dravet Syndrome requires ongoing care. It is essential for individuals with the condition to have regular check-ups with their doctor to monitor their progress and adjust treatment plans as needed. Seizures can sometimes change over time, and it is important to stay flexible with treatment options. The Best Approaches to Seizure Control While Dravet Syndrome can be challenging, there are many treatment options available. With the right combination of medications, diet, therapy and support, people with Dravet Syndrome can lead fuller lives. It is important to work closely with healthcare providers to find the best treatment plan for each individual.

Top COPD Inhalers for Better Breathing

Admin | April 1, 2021

Best COPD Inhalers Inhalers are designed to deliver medication directly to the lungs, helping to open airways, reduce inflammation and make it easier to breathe. Zemaira is an injectable medication that helps people with alpha-1 antitrypsin deficiency (a genetic condition that can worsen COPD). 1. Zemaira (α1-proteinase inhibitor) By increasing levels of the α1-proteinase inhibitor in the body, Zemaira helps protect the lungs from further damage. It's not a traditional inhaler, but it is an important treatment for people with specific COPD-related conditions. 2. Spiriva (tiotropium) Spiriva is one of the most commonly prescribed inhalers for people with COPD. It helps relax and open up the airways, making it easier to breathe. It is a long-acting bronchodilator, meaning it works for up to 24 hours, providing day-long relief. This inhaler is typically used once a day. [youmaylike] 3. Advair (fluticasone/salmeterol) Advair is a combination inhaler that contains both a steroid and a long-acting bronchodilator. The steroid works to reduce swelling and inflammation in the airways, while the bronchodilator helps relax the muscles around the airways. This combination helps improve breathing and prevent flare-ups of COPD symptoms. It’s typically used twice a day. 4. Symbicort (budesonide/formoterol) Like Advair, Symbicort is another combination inhaler with a steroid and a bronchodilator. It helps reduce inflammation in the lungs and opens the airways. This inhaler is also used to treat asthma, but it’s a great option for managing COPD as well. It is taken twice a day for the best results. 5. Breo Ellipta (fluticasone/vilanterol) Breo Ellipta is a once-a-day inhaler that combines a steroid and a long-acting bronchodilator. It helps open the airways and reduces inflammation in the lungs. This inhaler is typically used for people with chronic COPD symptoms to help improve lung function. 6. Albuterol (ProAir, Ventolin, Proventil) Albuterol is a short-acting bronchodilator that provides fast relief for sudden breathing problems, like shortness of breath or wheezing. It works quickly to open the airways, helping you breathe easier. It is often used as a rescue inhaler during flare-ups and should be kept on hand for emergencies. 7. Atrovent (ipratropium) Atrovent is another short-acting bronchodilator. It helps relax the muscles around the airways and can be used in combination with other medications to treat COPD. Atrovent is often used multiple times a day and can help reduce coughing and wheezing. COPD Control and Relief There are many inhalers available to help manage COPD symptoms, but the best one for you depends on your specific condition and treatment needs. Zemaira is an important option for people with alpha-1 antitrypsin deficiency, while other inhalers like Spiriva and Symbicort help open the airways and reduce inflammation. Speak with your doctor to find the right inhaler for you, and remember that proper use of your inhaler is key to managing your COPD and improving your quality of life. Read on to learn about exercise induced asthma, and how you can cope with it.

7 Treatment Options for Schizophrenia

Carlos Mendoza | April 1, 2021

Talk to your Doctor About Treatment for Schizophrenia Effective treatment for schizophrenia requires a combination of approaches tailored to each patient’s specific needs. Medication like Uzedy, therapy and lifestyle changes all play a role in managing symptoms, and help patients lead more stable, fulfilling lives. In this article we’ll look at common treatment options for schizophrenia 1. Antipsychotic Medications The cornerstone of treatment for schizophrenia is antipsychotic medication, like Uzedy. It's designed to reduce symptoms such as hallucinations, delusions and paranoia. Antipsychotics work by targeting neurotransmitters, particularly dopamine, which is often imbalanced in individuals with schizophrenia. They help stabilize thoughts and emotions, allowing people to better engage in daily activities and therapy. Uzedy (Risperidone Extended-Release Injection): Uzedy is a newer, long-acting injectable form of risperidone, which is particularly helpful for patients who struggle with adhering to a daily medication regimen. Given as a monthly or bi-monthly injection, Uzedy provides consistent medication levels, reducing the risk of symptom relapse. This can be particularly valuable for individuals with schizophrenia, as regular medication adherence is essential to symptom stability. Uzedy’s extended-release formulation allows the medication to work over time, reducing fluctuations and helping maintain a stable mood and thought pattern. Typical (first-generation) antipsychotics: These medications, such as haloperidol and chlorpromazine, were the first types of antipsychotics developed and are effective in controlling positive symptoms like hallucinations. However, they often come with side effects, including stiffness, tremors and tardive dyskinesia (involuntary muscle movements). These side effects can be difficult to manage, which has led to the development of newer, second-generation antipsychotics. Atypical (second-generation) antipsychotics: Newer antipsychotics, such as risperidone, olanzapine and aripiprazole, tend to have fewer side effects related to motor functions. They are often preferred because they also address both positive and negative symptoms of schizophrenia, such as emotional flatness or withdrawal. Although these medications also come with side effects, such as weight gain and metabolic changes, they are generally better tolerated than first-generation antipsychotics. [youmaylike] 2. Psychotherapy and Cognitive Behavioral Therapy (CBT) Medication is often combined with psychotherapy to improve outcomes. CBT, for example, helps patients recognize and change thought patterns that may contribute to symptoms. Through CBT, patients learn strategies to handle paranoia, manage delusions and cope with hallucinations. Therapy provides tools to differentiate between reality and perceptions shaped by schizophrenia, helping patients achieve a better quality of life. Social skills training and family therapy are also valuable, as they equip patients and their loved ones with coping mechanisms and communication skills. 3. Psychoeducation Education plays a critical role in managing schizophrenia. Psychoeducation programs inform patients and families about the condition, helping them understand symptoms, treatment options and coping strategies. Psychoeducation can include information on identifying early warning signs of relapse, understanding the side effects of medications, and managing daily stressors. Patients who are educated about their condition are often better able to manage symptoms and adhere to their treatment plan. 4. Supportive Housing and Vocational Rehabilitation For many individuals with schizophrenia, maintaining employment and independent living can be challenging. Supportive housing programs provide a structured, safe environment where residents receive assistance with daily activities, medication and social skills. Vocational rehabilitation programs, on the other hand, focus on helping individuals develop skills to find and maintain employment. These programs may offer job training, resume building, and interview preparation. Stable housing and vocational support contribute significantly to improved outcomes, providing a sense of purpose and routine. 5. Lifestyle Modifications and Self-Care While schizophrenia requires medical intervention, lifestyle choices also play a crucial role in managing symptoms. Regular physical activity, a balanced diet and adequate sleep are essential. Exercise can help improve mood, reduce anxiety and manage weight gain, a common side effect of antipsychotic medications. Diet is equally important; reducing sugar and unhealthy fats may help avoid metabolic complications associated with antipsychotic drugs. Additionally, sleep is vital for mental health, and establishing a routine can help improve both mood and cognitive function. 6. Long-Acting Injectable Antipsychotics (LAIs) Long-acting injectables like Uzedy provide an alternative for patients who struggle to take medication consistently. LAIs are administered every few weeks to months, ensuring stable levels of medication and reducing the likelihood of missed doses. LAIs can reduce the frequency of relapses and hospitalization, as they eliminate the need for daily pills. Some other examples include Abilify Maintena, Invega Sustenna and Aristada. For individuals prone to forgetting doses or struggling with self-management, LAIs can provide a more consistent and manageable form of treatment. 7. Electroconvulsive Therapy (ECT) For patients with severe symptoms that don’t respond to medication or therapy, electroconvulsive therapy (ECT) may be considered. ECT involves a brief electrical stimulation of the brain while the patient is under anesthesia, and it’s typically used when other treatments have failed. ECT has been shown to reduce severe symptoms, particularly catatonic symptoms and severe depressive states in patients with schizophrenia. It is usually a last resort and performed under careful medical supervision, but it can provide relief when other methods are ineffective.