Dravet Syndrome Seizure Treatment Options People with Dravet Syndrome often experience a variety of different types of seizures, including prolonged ones. To help, there's Fintepla, a medication approved to treat seizures caused by Dravet syndrome. Fintepla Fintepla works by targeting the brain’s electrical activity, helping to reduce the number and severity of seizures. Doctors prescribe Fintepla when other medications haven’t been effective in controlling seizures. This treatment has shown positive results in many patients, making it an essential option for managing Dravet syndrome. Medications for Dravet Syndrome Seizures Clobazam: This drug is often prescribed alongside other treatments. It helps to control seizures by calming the brain and reducing electrical activity. Valproate: This medication is used to control a variety of seizure types. However, it is not always the best choice for younger children due to its potential side effects. Topiramate: Used to prevent seizures, this medication works by affecting the brain's electrical signals. [youmaylike] Doctors may need to try different combinations of medications to find what works best for the individual. It’s important for patients and their families to closely monitor the medications and any side effects. Dietary Approaches: The Ketogenic Diet For some individuals with Dravet Syndrome, medications may not be enough to control seizures. In these cases, dietary treatments, such as the ketogenic diet, can be very helpful. The ketogenic diet is high in fats and low in carbohydrates, and it forces the body to use fat for energy instead of carbohydrates. This change in metabolism can help reduce seizures. The ketogenic diet should only be followed under the supervision of a doctor or dietitian, as it requires careful planning to ensure that the person gets the proper nutrition. Some children with Dravet Syndrome may experience a significant reduction in seizures after starting the ketogenic diet. Vagus Nerve Stimulation (VNS) Vagus Nerve Stimulation (VNS) is another treatment option for Dravet Syndrome. This therapy involves implanting a small device under the skin in the chest. The device sends electrical signals to the brain through the vagus nerve, which can help reduce the frequency and severity of seizures. The device can be programmed to give a burst of electrical stimulation when a seizure is detected, helping to stop the seizure or make it less severe. VNS is often considered when medications and diet do not provide enough seizure control. It is typically used in combination with other treatments. Surgical Options In some rare cases, surgery may be an option for treating Dravet Syndrome. If seizures are only coming from one part of the brain and medications do not help, surgery may be performed to remove that part of the brain. This surgery is called a lobectomy or hemispherectomy, depending on the area of the brain involved. Surgical options are not suitable for everyone, and doctors will carefully evaluate the risks and benefits before recommending surgery. Supportive Therapies While medications and other treatments are important for managing seizures, other therapies can be helpful in improving quality of life for individuals with Dravet Syndrome. These may include: Physical therapy: This helps improve mobility and strength, which can be affected by seizures. Occupational therapy: Helps individuals learn daily skills to live as independently as possible. Speech therapy: Helps improve communication skills, which may be affected by seizures. Ongoing Monitoring and Care Managing Dravet Syndrome requires ongoing care. It is essential for individuals with the condition to have regular check-ups with their doctor to monitor their progress and adjust treatment plans as needed. Seizures can sometimes change over time, and it is important to stay flexible with treatment options. The Best Approaches to Seizure Control While Dravet Syndrome can be challenging, there are many treatment options available. With the right combination of medications, diet, therapy and support, people with Dravet Syndrome can lead fuller lives. It is important to work closely with healthcare providers to find the best treatment plan for each individual.
Tethered Cord Syndrome
If you've never heard of tethered cord syndrome, it's likely because the condition is very rare, and thankfully so.
While this syndrome isn't typically dangerous, it can worsen if the condition is not seen. It can also cause permanent damage and diminish a person's ability to walk. But what is tethered cord syndrome?
In this article, we will briefly look at the symptoms of tethered cord syndrome, the causes, and the best ways to treat this neurological disease.
What is Tethered Cord Syndrome?
In this condition, the cord in tethered cord refers to the spinal cord.
The spinal cord is an essential component of the human body. It carries messages from the brain to all the other parts of the body through its bundle of nerves.
It occurs in a baby while it is in the womb. During development, the baby's spinal cord grows at the same pace as the other bones around it and is of the same length. But as the baby grows, the spine grows out.
But, in some cases, the spine becomes "tethered" when the cord's tail end becomes tied to the end of the body's spinal column. The spinal cord and the spine itself are different parts of the entire spine; remember that.
When the child is born, the tethered cord prevents the spinal cord from moving within the column. This doesn't affect the child as much until they start growing. Because the spinal cord cannot stretch, they start experiencing back pain and trouble walking.
Adults With Tethered Cord Syndrome
While some conditions typically become apparent in adulthood, this syndrome is not one of them.
Tethered cord syndrome is rare in adults and only occurs if the condition is not discovered or diagnosed during childhood.
Acquired tethered cord is also very rare among adults but can occur if any fatty mass at the spine's base becomes attached to the spinal cord's tip. This fatty mass can only develop if a patient has lipomyelomeningocele, a form of spina bifida.
What Are the Causes of Tethered Cord Syndrome?
There is no definitive cause of tethered cord syndrome. What we do know is that tethered cord occurs from birth with some children, and that a child with spina bifida may also have tethered cord syndrome.
Within the body, tethered cord syndrome occurs when the spinal cord end gets attached to something that doesn't let it move. What catches hold of it may include:
- Fat: Fat that grows around the spinal cord can catch it and grab hold.
- Bone: A piece of the spinal bone can attach to the spinal cord base.
- Scarring: If your child has back surgery, scars that form around the cord's bottom end can grab the spinal cord.
- Tight Ligament: This tight ligament is known as the filum terminale. This ligament is as thin as a string and is stretchy, but when tightened, it can catch and tether the spinal cord.
What Are the Symptoms of Tethered Cord Syndrome?
The most common symptoms of tethered cord syndrome include:
- Lack of bowel control: The child may have problems controlling their bowels because the nerves cannot stretch as much as they should.
- Lack of bladder control: For the same reason, because the child's spinal cord cannot stretch, the child may not feel when they want to urinate and would wet themselves without knowing.
- Back pain: The child may experience lower back pain and limited movement.
- Curved spine: Because the spinal cord is attached at the base, this may pull the spine down, causing the spine to curve.
- Trouble walking: While the child may not have issues walking before, they may begin experiencing issues walking as they grow up.
Diagnosing and Treating Tethered Cord Syndrome
If a parent notices these symptoms, their first step should be to take the child to the doctor. If the doctor suspects tethered cord syndrome, they will ask to run some tests to get a better picture of the child's spinal cord.
They may run an MRI and get a urology consultation to check if the child's bladder is affected. If results come back positive, the doctor will recommend surgery.
Treating Tethered Cord Syndrome With Surgery
While surgery may sound intimidating, it is necessary.
Surgery on the spine to correct a tethered cord is known as a laminectomy. And while this is major surgery, it's also common, so there's no need to worry. The laminectomy is compulsory if you want your child's spine fixed. If this operation is not done, it may make your child's condition even worse and result in permanent damage to the spine.
The Surgery Procedure
The patient will be given a general anesthetic, so they won't feel a thing.
During the operation, the doctor will make an incision on the patient's back and cut whatever element is tethering the cord. Once its hold is released and the cord returns to the spinal column, the surgeon will close up the incision.
This surgery takes three hours and requires a fair bit of surgical skill, so don't be concerned if your child doesn't come out within an hour.
After Care
The child will receive pain medication and fluids through IV and will be required to lie flat on their back for 2–3 days. Moving the child will be the nurse's responsibility, so you won't have to perform much care except feeding them.
Typically, children stay in the hospital for about a week, but that can vary depending on how severe their tethered cord was. Once the doctor feels comfortable knowing that the child can sit up, they'll allow you to take the child home.
Closing Thoughts
As a parent, you will worry about your child being in pain because of the tethered cord.
But, if you keep an eye on their health and report to the doctor if anything seems amiss, you may be able to catch this condition in time.