Dravet Syndrome Seizure Treatment Options People with Dravet Syndrome often experience a variety of different types of seizures, including prolonged ones. To help, there's Fintepla, a medication approved to treat seizures caused by Dravet syndrome. Fintepla Fintepla works by targeting the brain’s electrical activity, helping to reduce the number and severity of seizures. Doctors prescribe Fintepla when other medications haven’t been effective in controlling seizures. This treatment has shown positive results in many patients, making it an essential option for managing Dravet syndrome. Medications for Dravet Syndrome Seizures Clobazam: This drug is often prescribed alongside other treatments. It helps to control seizures by calming the brain and reducing electrical activity. Valproate: This medication is used to control a variety of seizure types. However, it is not always the best choice for younger children due to its potential side effects. Topiramate: Used to prevent seizures, this medication works by affecting the brain's electrical signals. [youmaylike] Doctors may need to try different combinations of medications to find what works best for the individual. It’s important for patients and their families to closely monitor the medications and any side effects. Dietary Approaches: The Ketogenic Diet For some individuals with Dravet Syndrome, medications may not be enough to control seizures. In these cases, dietary treatments, such as the ketogenic diet, can be very helpful. The ketogenic diet is high in fats and low in carbohydrates, and it forces the body to use fat for energy instead of carbohydrates. This change in metabolism can help reduce seizures. The ketogenic diet should only be followed under the supervision of a doctor or dietitian, as it requires careful planning to ensure that the person gets the proper nutrition. Some children with Dravet Syndrome may experience a significant reduction in seizures after starting the ketogenic diet. Vagus Nerve Stimulation (VNS) Vagus Nerve Stimulation (VNS) is another treatment option for Dravet Syndrome. This therapy involves implanting a small device under the skin in the chest. The device sends electrical signals to the brain through the vagus nerve, which can help reduce the frequency and severity of seizures. The device can be programmed to give a burst of electrical stimulation when a seizure is detected, helping to stop the seizure or make it less severe. VNS is often considered when medications and diet do not provide enough seizure control. It is typically used in combination with other treatments. Surgical Options In some rare cases, surgery may be an option for treating Dravet Syndrome. If seizures are only coming from one part of the brain and medications do not help, surgery may be performed to remove that part of the brain. This surgery is called a lobectomy or hemispherectomy, depending on the area of the brain involved. Surgical options are not suitable for everyone, and doctors will carefully evaluate the risks and benefits before recommending surgery. Supportive Therapies While medications and other treatments are important for managing seizures, other therapies can be helpful in improving quality of life for individuals with Dravet Syndrome. These may include: Physical therapy: This helps improve mobility and strength, which can be affected by seizures. Occupational therapy: Helps individuals learn daily skills to live as independently as possible. Speech therapy: Helps improve communication skills, which may be affected by seizures. Ongoing Monitoring and Care Managing Dravet Syndrome requires ongoing care. It is essential for individuals with the condition to have regular check-ups with their doctor to monitor their progress and adjust treatment plans as needed. Seizures can sometimes change over time, and it is important to stay flexible with treatment options. The Best Approaches to Seizure Control While Dravet Syndrome can be challenging, there are many treatment options available. With the right combination of medications, diet, therapy and support, people with Dravet Syndrome can lead fuller lives. It is important to work closely with healthcare providers to find the best treatment plan for each individual.
What Triggers Seizures?
This article will explore the common triggers of seizures, as well as a treatment option like FINTEPLA, a prescription medicine used to treat seizures associated with Dravet syndrome and Lennox-Gastaut syndrome. Dravet syndrome (DS) is a severe form of epilepsy characterized by frequent, prolonged seizures often triggered by high body temperature.
What is a Seizure?
The brain, comprising of nerve cells, communicates and functions by transmitting electrical activity from one nerve cell to another. This is how we are able to think, move and feel. When there is a disruption in electrical activity, this can affect our thoughts, feelings and movements. A seizure is an uncontrolled surge of electrical activity by the brain, which leads to changes in consciousness and involuntary movement of our muscles.
Seizures not only disrupt electrical activity but also disrupt oxygen transport and delivery. This is why, even though seizures usually resolve on their own, the aim is to prevent them from happening. Repeated seizures and seizures that occur for a prolonged period of time can lead to irreversible complications. The brain is one of the organs that continuously needs oxygen, and permanent brain damage can be observed in just minutes without an adequate oxygen supply. In severe cases, this can be life-threatening.
Seizure Symptoms
Seizures may present in various ways. The classic presentation of a person experiencing a seizure includes:
- Eyes that are rolled upward.
- Arms and legs exhibiting stiffening or jerking movements. This is due to the disruption in brain activity, which affects the muscles of the body.
- Sitting still and staring.
- Small, twitching movements in the fingers or face.
- A sudden stop in breathing or changes in breathing patterns.
- Loss of bowel and bladder control can lead someone to soiling themselves.
What Triggers a Seizure?
Once a seizure begins, there is little that can be done except wait for the seizure to cease or take the person to the nearest health facility. However, some seizures are more likely to occur under certain circumstances, wherein a pattern can be noted. In some cases, these situations can trigger a seizure, with increased chances of it happening. For people who have recurrent seizures, identifying these seizure triggers is helpful in seeing if a seizure might possibly happen and when these factors are removed, can the seizure be prevented. The following section discusses some common seizure triggers.
1. Stress
Although there are still debates as to whether or not stress can really trigger seizures, it is one of the most common factors perceived by people who experience recurrent seizures. Studies show that during periods of stress, there is an increase in the frequency of seizures experienced by patients with epilepsy. It is hypothesized that it can be due to the release of cortisol, which has excitatory properties that can further contribute to the occurrence of seizures.
2. Sleep Problems
Sleep problems have also been considered as another seizure trigger. Lack of sleep and disrupted sleep were found to contribute to the occurrence of seizures, even in the absence of other triggers or factors. Poor quality of sleep has also been perceived by patients to trigger some seizures, although data is not as strong compared to the quantity of sleep. Sleep deprivation as a seizure trigger is due to its effect on gamma-aminobutyric acid (GABA) receptors. Some studies show that treatment of sleep problems also results in fewer occurrences of seizures.
3. Flashing Lights and Bright Lights
Exposure to bright lights or flashes of light can also cause seizures. This occurs in around
3% of people with epilepsy. This kind of epilepsy is called photosensitive epilepsy.
Examples of light sources that can trigger seizures include:
- Light from television screens or computer monitors.
- Strobe lights.
- Flashing lights in vehicles.
- Natural light or sunlight.
Avoiding these can be helpful in reducing the occurrence of seizures in susceptible patients.
When seeing a seizure, it can look scary at first. Most people panic when they see someone experiencing a seizure episode. However, knowing how to deal with this medical situation and knowing how to identify seizure triggers can be extremely helpful and lifesaving.
In Conclusion
Seizures are one of the most well-documented symptoms everyone is familiar with. It is one of the symptoms commonly shown in movies and shows and the most common acute neurologic problem in the U.S. Data shows that around 1 in 10 people will have a seizure not caused by an injury, such as a concussion, illness, or infection. This might make you ask, “What triggers seizures?" First, you need to understand that recurrent seizures, also known as epilepsy, are the third most common serious neurologic disorder and occur in 1 in 26 people. Around 3.4 million Americans live with this condition.
Although many people know what a seizure is, not everyone knows what to do when it happens, and even fewer know that some seizures can be anticipated or preempted. Knowing when a seizure will occur is important to prepare appropriately, and in some cases, even prevent seizures from happening. This article will discuss what a seizure is, what the symptoms of a seizure are and what triggers seizures.