Before the Needle Although many people have heard about Botox, few people know what it actually is. So, what are Botox injections? Many people would be surprised to learn that it actually is a drug derived from a neurotoxin created by a specific bacterium, the Clostridium botulinum. This is the same toxin that causes botulism, a life-threatening form of food poisoning. When ingested in its natural form, Botox can cause paralysis that spreads through the body until it eventually works its way to the breathing muscles, causing respiratory failure. This is why it is important to educate yourself before considering Botox injections. Why Do People Get Botox? Although this is a toxin, it is safe to use in small doses for medical use. Doctors often use the substance cosmetically. It is probably best known as an anti-wrinkle agent used to treat fine lines and signs of aging. Most commonly, it is used to treat wrinkles in the neck or face. Some people also get Botox injections to minimize their forehead lines. [youmaylike] In addition to smoothing skin to give it a more youthful appearance, it serves other medical purposes. Some patients use it to treat severe underarm sweating, migraines, uncontrollable blinking, overactive bladder and strabismus (misaligned eyes). How Does Botox Work? Botox causes paralysis. While this can be fatal in large, targeted doses, it is the property that helps with treatment. It acts locally, upon the injection site where it will weaken or paralyze targeted muscles. This is done as the neurotoxin attaches to nerve ending and blocks impulses from coming through. Instead of contracting as normal, the injected tissues will remain relatively frozen. Reducing the pulling of the skin is what makes the skin look more youthful. This signal-blocking property is also assisted with the other medical applications of Botox. It is important to realize that these are not the same as a filler. How Long Does Botox Last? The effects of Botox do not last forever. After a while, the signals will begin to pass through again. Procedures are expected to have a visual effect that lasts three to six months. Botox will not lose its effect overnight. Rather, you will experience a gradual decline in results as the muscles slowly regain their movement. The effects of your first session will wear off faster than the later sessions. Your first session is expected to last around three months where the later sessions will gradually last up to six months. Is Botox Safe? Under controlled medical environments, Botox injection procedures are considered low-risk. Most procedures are carried out safely and effectively with little side effects. The side effects one does experience are normally what is expected from any sort of injection procedure. This would be some temporary redness, bleeding or bruising at the injection site. In rare cases, one may experience a headache in the first two days after the procedure or temporary drooping. With this being said, there are certain situations where you should avoid getting Botox injections. You should not undergo treatments if you: Are 65 years of age or older, or under 18 years old. Have breathing problems. Have bleeding problems. Are allergic to or have sensitivities to Botox products. Be sure to talk to your doctor about any medications or supplements you are currently taking as there may be some interactions that could be dangerous. If you immediately experience signs of an allergic reaction upon the treatment, seek medical help immediately. To reduce any of the potential complications, it is important that you thoroughly research the performing physician. You need to make sure you are going to someone who knows what they are doing and has an adequate environment to perform hygienically and legally. It is not worth the risk to seek other methods. Does Botox Hurt? Botox procedures use very tiny needles. While injections are associated with some pain, the size of the needles keeps this pain at a minimum. Botox injections are generally preceded by some sort of anesthetic treatment to numb the pain. This is often done with a topical anesthetic cream or a cold pack. Most people report minimal to no pain at all. The Cost of Botox The cost of Botox will vary greatly depending on the specifications of your procedure. Some facilities will charge you by the area covered, but more often they charge you per unit of Botox used. On average, you will pay about $20 per unit. As the average treatment is about 20 to 60 units on average, you will likely pay between $500 and $800. The number of units used in a session will vary greatly depending on the space that you want to be covered. The bigger the area, the more units you will need to pay to achieve results. When it comes to cosmetic procedures, insurance will likely not pay for any of the costs. You can talk with your insurance provider to find out if they offer financial compensation for non-cosmetic procedures.
Stage 3 Kidney Disease Explained
In this article we look at the most common symptoms of kidney disease. If you've ever wondered, “what is stage 3 kidney disease?” then you are in the right place.
Do you think you or someone you know might have it? This article will explain what kidney disease is, the causes and symptoms, and we will go over how someone can get a proper diagnosis and begin treatment.
Symptoms of Kidney Disease
The early stages of kidney disease may not have any noticeable signs or symptoms. However, as kidney disease progresses, more symptoms are evident. Usually, when symptoms of kidney disease appear, there is a significant loss of kidney function.
Some of the symptoms are nonspecific or can be a result of other diseases, but other risk factors can lead to a suspicion of kidney disease. Symptoms of late stage kidney disease may include:
- Headaches
- Loss of appetite
- Nausea or vomiting
- Weight loss
- Itching or numbness of the skin
- Fatigue, or feeling tired most of the time
- Changes in behavior or sensorium
- Chest pain
- Shortness of breath
- Pallor or anemia (low hemoglobin count)
- Decreased amount of urination
- Sleep problems
- Swelling of extremities or generalized swelling
Understanding Kidney Disease
Put simply, kidney disease occurs when there is damage to the kidneys. The kidneys are bean-shaped organs that are responsible for the filtration of blood and remove waste through the production and excretion of urine.
Kidney disease can be acute or chronic. Acute kidney disease usually lasts days or weeks, while chronic disease lasts months to years. As a person gets older, the chances of getting kidney disease increases, especially if that person has any risk factors, which may include:
- Comorbidities such as hypertension, diabetes, or cardiovascular disease
- Smoking
- Obesity
- Family history of kidney disease
- Congenital disorders or abnormal structure of the kidney
- Old age
It is important to detect kidney disease early so that appropriate treatment can begin. This will help prevent permanent damage to your kidneys and help avoid life-changing treatment, such as dialysis.
What Causes Kidney Disease?
There are many different causes of kidney disease. Some are genetic, while others are acquired or due to a person’s environment and lifestyle.
The most common causes of kidney disease include diabetes and high blood pressure. Diabetes causes kidney disease by damaging the filters of the kidney, which leads to the leaking of important substances, such as a protein that is needed by the body.
Hypertension causes kidney disease by damaging the blood vessels of the kidney. These injuries make the kidney do a poor job of filtering wastes and in severe cases leads to the buildup of harmful toxins in the body.
Other causes of kidney disease may be infections, toxins, drugs, or congenital or autoimmune diseases. Examples of other causes of kidney disease may include:
- Autoimmune diseases, such as Goodpasture’s disease or nephritis from lupus
- Genetic conditions, such as Alport syndrome or polycystic kidney disease
- Infections and their complications, such as pyelonephritis or glomerulonephritis
- Drugs or toxins, such as lead poisoning
- Renal artery stenosis
Stages of Kidney Disease
Chronic kidney disease is when there is an irreversible injury to the kidneys over a long period. It has five different stages which represent the condition and function of the kidney.
Stage 1 kidney disease occurs when the disease has just begun, and stage 5 indicates complete kidney failure. As the disease progresses, your kidneys have a harder time filtering your blood, and if it progresses to stage 5, they stop functioning altogether.
According to the American Kidney Fund, stage 3 kidney disease occurs when a patient’s estimated glomerular filtration rate (eGFR) is between 30 and 59. There is moderate kidney damage, but they are still able to function.
Symptoms do not usually show in stage 3 kidney disease. However, if you experience any swelling in the hands or feet, back pain, or frequent urination, it could be an indication. Don’t hesitate to make an appointment with your doctor if you feel like something is off.
Stage 3 Kidney Disease Diagnosis
During stage 3, the damage to the kidneys is moderate and the loss of kidney function is evident. As mentioned above, a patient’s eGFR values are found to be in the range of 30 to 59.
Other laboratory examinations can be used to determine kidney disease as well. These include checking a protein called albumin in your urine, which is not usually present in patients with normal kidneys. Albumin is normally filtered and stays in the blood, but in patients with kidney disease, due to the damage to the kidneys, it leaks out. Checking the albumin not only helps determine if kidney disease is present, but also evaluates response to treatment.
A patient’s kidneys can also be evaluated through imaging, especially if the cause may be genetic.
Is it the end of the world if you are diagnosed with stage 3 kidney disease? Despite having a noticeable change in kidney function, there are still things that can be done.
The goal for patients with this stage of kidney disease is to avoid further progression. Kidney disease will worsen over time if nothing is done to prevent its progression. This is important because kidney damage can be permanent.
Treatment Options for Kidney Disease
It is important to identify kidney disease because early detection can prevent progression to irreversible kidney damage. Stage 3 kidney disease can usually be cured without dialysis or a kidney transplant.
There are medical and non-medical options for kidney disease, but the goals of therapy are to treat the underlying cause and to prevent further progression of kidney disease. Medications to control hypertension and diabetes are wide and varied. Other medications to treat other causes of kidney disease are also available (for example, antibiotics for infection).
Further medications can be given for complications of kidney disease (iron supplements for patients with anemia, calcium supplements, and medications to induce urination for those with decreased urine). A consult with a nephrologist who specializes in kidney disease is also important.
Non-medical options include changing diet and lifestyle. These include decreasing salty food intake, increasing physical activity, stopping smoking, and stay within the ideal body weight. These changes are important for patients with Stage 3 kidney disease because they will help halt progression.