Dravet Syndrome Seizure Treatment Options People with Dravet Syndrome often experience a variety of different types of seizures, including prolonged ones. To help, there's Fintepla, a medication approved to treat seizures caused by Dravet syndrome. Fintepla Fintepla works by targeting the brain’s electrical activity, helping to reduce the number and severity of seizures. Doctors prescribe Fintepla when other medications haven’t been effective in controlling seizures. This treatment has shown positive results in many patients, making it an essential option for managing Dravet syndrome. Medications for Dravet Syndrome Seizures Clobazam: This drug is often prescribed alongside other treatments. It helps to control seizures by calming the brain and reducing electrical activity. Valproate: This medication is used to control a variety of seizure types. However, it is not always the best choice for younger children due to its potential side effects. Topiramate: Used to prevent seizures, this medication works by affecting the brain's electrical signals. [youmaylike] Doctors may need to try different combinations of medications to find what works best for the individual. It’s important for patients and their families to closely monitor the medications and any side effects. Dietary Approaches: The Ketogenic Diet For some individuals with Dravet Syndrome, medications may not be enough to control seizures. In these cases, dietary treatments, such as the ketogenic diet, can be very helpful. The ketogenic diet is high in fats and low in carbohydrates, and it forces the body to use fat for energy instead of carbohydrates. This change in metabolism can help reduce seizures. The ketogenic diet should only be followed under the supervision of a doctor or dietitian, as it requires careful planning to ensure that the person gets the proper nutrition. Some children with Dravet Syndrome may experience a significant reduction in seizures after starting the ketogenic diet. Vagus Nerve Stimulation (VNS) Vagus Nerve Stimulation (VNS) is another treatment option for Dravet Syndrome. This therapy involves implanting a small device under the skin in the chest. The device sends electrical signals to the brain through the vagus nerve, which can help reduce the frequency and severity of seizures. The device can be programmed to give a burst of electrical stimulation when a seizure is detected, helping to stop the seizure or make it less severe. VNS is often considered when medications and diet do not provide enough seizure control. It is typically used in combination with other treatments. Surgical Options In some rare cases, surgery may be an option for treating Dravet Syndrome. If seizures are only coming from one part of the brain and medications do not help, surgery may be performed to remove that part of the brain. This surgery is called a lobectomy or hemispherectomy, depending on the area of the brain involved. Surgical options are not suitable for everyone, and doctors will carefully evaluate the risks and benefits before recommending surgery. Supportive Therapies While medications and other treatments are important for managing seizures, other therapies can be helpful in improving quality of life for individuals with Dravet Syndrome. These may include: Physical therapy: This helps improve mobility and strength, which can be affected by seizures. Occupational therapy: Helps individuals learn daily skills to live as independently as possible. Speech therapy: Helps improve communication skills, which may be affected by seizures. Ongoing Monitoring and Care Managing Dravet Syndrome requires ongoing care. It is essential for individuals with the condition to have regular check-ups with their doctor to monitor their progress and adjust treatment plans as needed. Seizures can sometimes change over time, and it is important to stay flexible with treatment options. The Best Approaches to Seizure Control While Dravet Syndrome can be challenging, there are many treatment options available. With the right combination of medications, diet, therapy and support, people with Dravet Syndrome can lead fuller lives. It is important to work closely with healthcare providers to find the best treatment plan for each individual.
What is Hyperkalemia?
Hyperkalemia is the medical term for when you experience high potassium levels in your blood.
In terms of numbers, a healthy individual will have between 3.6mmol/L and 5.2mmol/L in their body. Anything higher than that is officially classified as hyperkalemia.
- Between 5.3mmol/L and 6.0mmol/L is mild hyperkalemia.
- Between 6.1mmol/L and 7.0 mmol/L is moderate hyperkalemia.
- Above 7mmol/L is severe hyperkalemia.
Why is Too Much Potassium Harmful?
Potassium is healthy for you in the right doses. Your body needs it to function properly. It is an incredibly important substance that plays a vital role in your nerves and muscle cells. This means that you need it for your heart to work.
Like with anything else, too much of a good thing is not good. The more common form of hyperkalemia only rears mild to moderate symptoms. The most extreme severities of this condition can result in death.
Symptoms of Hyperkalemia
Generally, until your hyperkalemia is severe, you may not even experience or recognize any of the symptoms. As your levels soar to dangerous heights, you may experience one or more of the following symptoms:
- Muscle weakness or pain. Your muscles may feel tender or even painful. It may feel as though you just finished an intense workout.
- Fatigue. Despite getting adequate sleep, you may feel sluggish and tired the entire day or you may be too weak to function.
- Nausea. An upset stomach may or may not be accompanied by some vomiting. This is a common sign of hyperkalemia.
- Breathing problems. You may find it difficult to take deep breaths or find yourself forced to gasp for air.
- Irregular heartbeat. Your heart may beat funnily or feel weird in your chest. This is always a symptom to bring up to your doctor immediately.
- Chest pains. Chest pains ranging from mild to severe are a common result of hyperkalemia. In the most extreme cases, hyperkalemia left untreated can cause cardiac arrest and death.
What Causes Hyperkalemia?
There are several known causes of hyperkalemia, which range from medical disorders to lifestyle habits. Hyperkalemia is known to have many causes. These include:
Kidney Disease
The main function of a kidney is that it filters everything in your body. When there is something wrong with your kidneys, it can mess up all sorts of vitamin levels in your body. Potassium is just one of them.
Heart Disease
Heart disease results in a variety of factors that make it more likely to have problems with your potassium levels.
Hormone Imbalances
Having abnormally low amounts of aldosterone can result in potassium problems. This can happen due to a variety of conditions, including hypoaldosteronism and congenital adrenal hyperplasia.
Diabetes
A lack of insulin may be the culprit behind enhanced potassium levels. This is something that would be more likely to occur if diabetes is undermanaged (or undiagnosed).
Medications
Side effects of certain medications could cause potassium levels to rise. You may be surprised to see that some common medications will do this. Non-steroidal, anti-inflammatory drugs, such as ibuprofen and naproxen, will do it. Some of the other medications that can do this are heparin, mannitol, beta-blockers, angiotensin inhibitors, calcium blockers, and cyclosporine.
Diet
Medications are not the only way to introduce potassium to the body. There are lots of foods that can lead to heightened potassium levels. Many of these foods are healthy, but to a person at risk for hyperkalemia, they can be dangerous if not eaten in responsible quantities.
There is also the chance that you are a victim of pseudo hyperkalemia. As the name suggests, you do not have any potassium problems. Sometimes due to faulty equipment, you will get a wrong reading.
Hyperkalemia Treatment
To determine how to treat hyperkalemia, it is important that you first identify the cause of it in yourself. Getting advice from a licensed medical physician is the best way to determine your treatments.
Diet Change
Changing your diet can do wonders for your health. If you battle hyperkalemia, consider limiting your intake of foods rich in potassium like cucumbers, pumpkins, potatoes, bananas, grapefruit, oranges, eggplants and peas.
Intravenous Calcium or Insulin and Glucose
Medical injections are an efficient and fast technique to lower calcium levels. When diet alone is not enough, these can drop your potassium levels to a safer place in a pinch.
Albuterol
Doctors may also administer albuterol alone or in addition to other treatments. Unfortunately, this does not work for everyone.
Changing Medications
If a certain medication is causing dangerous, unwanted side effects, you may want to talk to your doctor about switching.
