Dravet Syndrome Seizure Treatment Options People with Dravet Syndrome often experience a variety of different types of seizures, including prolonged ones. To help, there's Fintepla, a medication approved to treat seizures caused by Dravet syndrome. Fintepla Fintepla works by targeting the brain’s electrical activity, helping to reduce the number and severity of seizures. Doctors prescribe Fintepla when other medications haven’t been effective in controlling seizures. This treatment has shown positive results in many patients, making it an essential option for managing Dravet syndrome. Medications for Dravet Syndrome Seizures Clobazam: This drug is often prescribed alongside other treatments. It helps to control seizures by calming the brain and reducing electrical activity. Valproate: This medication is used to control a variety of seizure types. However, it is not always the best choice for younger children due to its potential side effects. Topiramate: Used to prevent seizures, this medication works by affecting the brain's electrical signals. [youmaylike] Doctors may need to try different combinations of medications to find what works best for the individual. It’s important for patients and their families to closely monitor the medications and any side effects. Dietary Approaches: The Ketogenic Diet For some individuals with Dravet Syndrome, medications may not be enough to control seizures. In these cases, dietary treatments, such as the ketogenic diet, can be very helpful. The ketogenic diet is high in fats and low in carbohydrates, and it forces the body to use fat for energy instead of carbohydrates. This change in metabolism can help reduce seizures. The ketogenic diet should only be followed under the supervision of a doctor or dietitian, as it requires careful planning to ensure that the person gets the proper nutrition. Some children with Dravet Syndrome may experience a significant reduction in seizures after starting the ketogenic diet. Vagus Nerve Stimulation (VNS) Vagus Nerve Stimulation (VNS) is another treatment option for Dravet Syndrome. This therapy involves implanting a small device under the skin in the chest. The device sends electrical signals to the brain through the vagus nerve, which can help reduce the frequency and severity of seizures. The device can be programmed to give a burst of electrical stimulation when a seizure is detected, helping to stop the seizure or make it less severe. VNS is often considered when medications and diet do not provide enough seizure control. It is typically used in combination with other treatments. Surgical Options In some rare cases, surgery may be an option for treating Dravet Syndrome. If seizures are only coming from one part of the brain and medications do not help, surgery may be performed to remove that part of the brain. This surgery is called a lobectomy or hemispherectomy, depending on the area of the brain involved. Surgical options are not suitable for everyone, and doctors will carefully evaluate the risks and benefits before recommending surgery. Supportive Therapies While medications and other treatments are important for managing seizures, other therapies can be helpful in improving quality of life for individuals with Dravet Syndrome. These may include: Physical therapy: This helps improve mobility and strength, which can be affected by seizures. Occupational therapy: Helps individuals learn daily skills to live as independently as possible. Speech therapy: Helps improve communication skills, which may be affected by seizures. Ongoing Monitoring and Care Managing Dravet Syndrome requires ongoing care. It is essential for individuals with the condition to have regular check-ups with their doctor to monitor their progress and adjust treatment plans as needed. Seizures can sometimes change over time, and it is important to stay flexible with treatment options. The Best Approaches to Seizure Control While Dravet Syndrome can be challenging, there are many treatment options available. With the right combination of medications, diet, therapy and support, people with Dravet Syndrome can lead fuller lives. It is important to work closely with healthcare providers to find the best treatment plan for each individual.
Symptoms of Poor Circulation
In this article, we will focus on the symptoms of poor circulation and when you should seek medical help.
Signs of Poor Circulation
1. Varicose Veins
If the valves in the veins of the legs are damaged, your blood will find it difficult to get back to the heart. This results in engorged veins and will eventually cause varicosities in the legs. Varicose veins are more common to those who regularly stand for long periods.
2. Painful Muscle Cramping
The most common symptom of poor circulation is claudication, described as muscle discomfort or painful cramping, particularly in the legs. This is felt when you exercise or walk and usually disappears after resting your legs. The muscles that are most involved are the hips, thighs or calves.
Claudication happens if there is a hindrance to the normal blood flow. For example, in atherosclerosis, where there is a buildup of cholesterol plaques in the blood vessels, the muscles cannot get enough blood during physical activity. The cramping pain is the muscle’s way of warning you that it is not getting enough blood during exercise to meet its increased demand.
3. Numbness or Weakness
Reduced blood flow to different body parts may cause slow and irreversible damage to the nerves, which may be felt as tingling, numbness or weakness in that area. This is particularly alarming because having numbness on the extremities decreases your skin’s sensitivity to pain. As a result, there may be instances where your skin has already been damaged or wounded, but you cannot feel it.
4. Temperature Differences in the Extremities
Poor circulation can lead to fluctuations in your skin’s temperature regulation. For example, reduced blood flow to your hands or feet may make them colder than the other parts of your body. To assess the temperature of your skin, you can use the back of your hands for a more accurate assessment.
5. Wounds That Do Not Heal or Heal Slowly
Wounds heal by the different components and cells delivered through the bloodstream to the affected area. When blood flow is compromised, the healing process takes much longer and may even lead to infections. Even the slightest break in the skin may lead to catastrophic changes that could lead to amputation, especially in people with diabetes.
6. Change of Skin Color
When there is insufficient blood flow, the skin may appear pale or blue (cyanosis). The change of color in the skin indicates that the oxygen-rich blood is unable to reach those tissues. The commonly affected body parts that may have this symptom are the toes, fingers, palms, soles and lips.
7. Poor Hair or Nail Growth
Hair and nails need the nutrients in your body to keep them healthy. Nutrients are delivered to the hair and nails through the blood. Therefore, any blockage or hindrance of the normal circulation of blood may affect the growth of healthy hair and nails, which can lead to hair loss or poor nail growth.
8. Shiny Skin on Legs
Shiny skin on the legs can indicate that the skin stretched due to excess fluids in the legs. Poor circulation can cause blood pooling in the legs, resulting in fluid leakage from the blood vessels to the surrounding tissues. In turn, the skin will stretch, giving it a shiny appearance.
9. Weak Pulses
When blood flow is restricted, the usual, brisk pulses on the extremities become weaker. Doctors usually include this in their physical examination to rule out any peripheral arterial disease.
10. Erectile Dysfunction in Men
The penis is made up mostly of blood vessels. Penile erection happens because the arteries of the penis are filled up with blood to elongate and stiffen the organ. When there is poor circulation, blood cannot fill up the blood vessels in the penis. Most cases of impotence are a complication primarily of the arterial system.
What is Poor Circulation?
Poor circulation is not a condition in itself, but having any of its symptoms may indicate more serious conditions, such as:
- Peripheral artery disease (PAD).
- Uncontrolled diabetes.
- Blood clots.
- Atherosclerosis (buildup of fatty deposits in the vessels).
- Heart conditions.
Having poor circulation may not be apparent initially. Still, whether you experience symptoms or not, it is important to be aware of them early on to help detect the underlying cause. For example, smoking, a sedentary lifestyle and obesity are all factors that increase the likelihood of a person experiencing poor circulation symptoms.
In Review
The symptoms of poor circulation may vary for each person. In general, conditions that cause poor circulation are easier to treat when your doctor detects it early. If you experience any of these symptoms and suspect that it may be caused by a dysfunction in your normal blood circulation, it is essential that you see your doctor for assessment and treatment right away.